It's not a comic or game but Quasimodo from the Hunch Back of Notredam(sp?) is a pretty famous one. I think it's sad that our (particularly Western) culture leads to the favouring and rejection of based on physical appearance; an ingrained presumption that 'pretty people are better than ugly people'. Though I say this I know I'm being a hypocrite; I judge people based on apearance as much as anyone else,it is still regretable.